News Blog

Meet us at the next NUM 2024 being held 22 – 23 of October in Munich, Germany!

The Nanion User Meeting (NUM) is a platform for sharing and learning from the experts and peers in the fields of drug discovery, assay development, cardiac safety, ion channels and transporters, automated patch clamp, cell analytics, and beyond.

Ensuring Safety and Quality of Botanical Extracts in Food and Dietary Supplements

safety and quality of botanical extracts in food and dietary supplements? This critical question was at the heart of the discussions at the Botanical Safety Consortium Summit, where our CEO, Matthias Gossmann, was co-presenting the important work of the Cardiotox Working Group alongside experts Shane R. Zhao, André Monteiro da Rocha and Joseph C. Wu. Together, we are driving forward collaborative efforts to address the safety concerns surrounding botanical ingredie

innoVitro will participate in the 2024 BSC Summit, held from October 10–12 at NIEHS in Durham, NC, USA.

The summit will focus on updates from the working group regarding the evaluation of new approach methodologies (NAMs) tested for their suitability for botanicals. In addition the event will feature discussions on the current tool-kit, identify gaps and future research priorities.

Join us for the third LabINAR BREAK to discuss chamber-specific hiPSC-cardiomyocytes and their value for preclinical drug discovery!

In this session, Jamie Bhagwan from Axol Bioscience Ltd. will present a pharmacological characterization of atrial and ventricular hiPSC-derived cardiomyocytes regarding contractile properties. Substances tested include GPCR targeting compounds and ion channel modulators.

Meet us at the Safety Pharmacology Society Annual Meeting in sunny San Diego, USA

Join us at this great event from September 22-25, and visit our booth No. 204! Stay tuned for more information regarding posters, presentations and partner talks!

Meet us at the Eurotox 2024 in Copenhagen, Denmark

The congress will take place from 8 to 11 September 2024. We are looking forward to meeting you there.

Join us for our 𝗟𝗮𝗯𝗜𝗡𝗔𝗥 𝗕𝗥𝗘𝗔𝗞 𝟮 webinar on the value of human-based cardiac fibroblast models for preclinical screening assays!

In this session, Ravi Vaidyanathan from FUJIFILM Cellular Dynamics, Inc will demonstrate how 2D and 3D co-culture systems enhance the relevance of these cell models, bridging the gap between lab research and clinical success.

Meet us at the 3rd Microphysiological Systems World Summit (MPS) in Seattle, USA

Visit our booth at the 3rd MPS World Summit taking place in the Seattle Convention Center, from June 10th to 14th, 2024. Stay tuned for more information regarding posters and presentations.

Meet us at the Society of Toxicology in Salt Lake City, USA

Get ready to meet us at the 63rd SOT Annual Meeting & ToxExpo in Salt Lake City, March 10-14th, 2024. Stop by our booth 1832 to learn about our cell-based assay services!

Cardiac Safety Committee Recognition Award 2022 -2023

We are happy to announce innoVitro’s CTO Peter Linder has been awarded the HESI Cardiac Safety Committee Recognition Award 2022 – 2023 for his exceptional contributions to the Stem Cell Working Group.

Meet us at the Nanion User Meeting

The Nanion User Meeting will be held October 24 – 25 in Munich, Germany.

Meet us at the Safety Pharmacology Society Annual Meeting

The Safety Pharmacology Society (SPS) meeting will be held Septemeber 18 – 21 at the SQUARE Brussels Meeting Centre in Belgium. Stop by our booth No. 505 as well as poster and oral presentations

Meeting with Ärzte gegen Tierversuche

We had a great time welcoming Tamara Zietek from Ärzte gegen Tierversuche e.V. at our headquarter in Jülich to show her innoVitro’s CRO service laboratories and technologies and to discuss new approach methodologies as a valid replacement for animal models.

Meet us at the 2nd Microphysiological System World Summit in Berlin, Germany!

The MPS conference will take place June 26 – 30, 2023 in the JW Marriott Hotel Berlin. Click here for more information https://mpsworldsummit.com/ and keep an eye out news coming soon!

Meet us at the 62nd Society of Toxicology Annual Meeting in Nashville, USA

The SOT conference will take place in March 19 – 23, 2023. Keep an eye out for more information coming soon!

Meet us at the XVIth International Congress of Toxicology (ICT), September 18 – 21, 2022 in Maastricht, Netherlands

Meet us at the innoVitro Booth 51 in Maastrichts Expositie en Congres Centrum (MECC), September 18th – 21st, 2022.

We will also present a poster (No 456) entitelt „Chronic Compound Analysis of hiPSC-CMs in a Physiological Environment for Preclinical Cardiac Risk Evaluation: Defined Serum-Free Medium and Long-Term Culture on the FLEXcyte 96“.

We are looking forward to seeing you at the conference!

Safety Pharmacology Society Annual Meeting, September 11 -14, 2022 in Montréal, Canada

Meet us at the innoVitro Booth 810 in Montréal, Canada at the Safety Pharmacology Society Annual Meeting in September 2022!

Don’t miss our poster presentations entitelt (SP090) „Lot-to-lot consistency study of commercial human iPSC derived cardiomyocytes regarding contractile properties“ and (SP091) „Assessment of a Smooth Muscle Cell Maturation Protocol for the Analysis of Contractile Properties“.

We are looking forward to seeing you at the SPS 2022!

innoVitro awarded as most innovative in vitro technology company in Germany

innoVitro has been recognized by GHP (Global Health & Pharma) as most innovative in vitro technology company in Germany for the year 2022.

innoVation Facts – Cardiac Maturation Cues (Part 3)

The last part of our innoVation Facts series dealing with cardiac maturation cues focused on gene expression analysis of human iPSC-derived cardiomyocytes (hiPSC-CMs) cultured either on physiological FLEXcyte or regular cell culture plates.

The data shows increased expression levels of ACTC1 and ACTN2 genes (both producing cytoskeleton-related proteins) as well as the MYH7 gene (important for cardiac contraction) when hiPSC-CMs are plated on physiological FLEXcyte plates that resemble in vivo conditions of the human heart.

These changes in expression of genes relevant for contraction and cytoskeleton substantiate the phenotypic and functional changes of hiPSC-CMs shown in part 1 and 2 where mature actin structures and an increased contraction amplitude was shown.

innoVation Facts – Cardiac Maturation Cues (Part 2)

In our second part of the innoVation Facts series addressing cardiac maturation cues, we focus on phenotypic changes that take place when human iPSC-cardiomyocytes (hiPSC-CMs) are cultured on FLEXcyte 96 plates to emulate the physiological conditions of the human heart.

To visualize changes in actin filament development, staining with Phalloidin was performed on Cardiosight-s (Nexel Ltd.) hiPSC-CMs plated on FLEXcyte 96 plates for 7 days and 17 days. (Scale bars = 20µM)

The staining shows a clear change in actin development from fine structures at days 7 to more pronounced filaments including typical striation, indicating the establishment of sarcomers (Fritz-Six et al., 2003; Chu et al., 2003; Ehler et al., 2004).

innoVation Facts – Cardiac Maturation Cues (Part 1)

We are happy to announce our new innovation facts blog focussing on news about the FLEXcyte technology and related topics!

We start the blog with a series about cardiac maturation cues, a hot topic for everyone working on human iPSC-derived cardiomyocytes.

In this first part, we show you how to use the physiological environment of the FLEXcyte plate over time to push maturation in vitro.

What is your research focus? Get in contact to discuss your work, we are happy to support!