Category: innoVation

We keep the focus on reviews this month, with one that has summarized current maturation methods for human induced pluripotent stem cell-derived cardiomyocytes. Read the review to learn about maturity evaluation of human iPSC-derived cardiomyocytes in comparison to adult cardiomyocytes and how prolonged culture time, biochemical cues, cellular interaction, 3D cell-culture, and of course substrate…Continue readinginnoVation Series – Research Article of the Month – May 2021

This months article is an intersting review that summarizes the current understanding of potential cardiovascular toxicities of CD19-specific Car T cell therapies. CD19-specific chimeric antigen receptor (CAR) T cell therapies have shown remarkable early success in highly refractory and relapsing hematological malignancies. However, most significant side effects of the therapy are cytokine release syndrome (CRS)…Continue readinginnoVation Series – Research Article of the Month – April 2021

This month’s innovation series research article was published from our colleagues at the University of Cologne last week. Find out how you can optimize cardiac differentiation out of human induced pluripotent stem cells. This biomimetic approach is based on poly(dimethylsiloxane) (PDMS) substrates with similar stiffness to the native heart and a well-defined surface chemistry obtained…Continue readinginnoVation Series – Research Article of the Month – March 2021