Resources

Documents

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Technical Documentation

221012 FLEXcyte iCELL Handling GuideDownload

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AppNotes

Positive inotropic effects in human iPSC-derived cardiomyocytes can be triggered through a flexible pro-maturation environmentDownload
Chronic cardiotoxic effects of tyrosine kinase inhibitors and anthracyclines analyzed with the FLEXcyte 96 on human iPSC-derived cardiomyocytesDownload
FLEXcyte 96 recordings in comparison to in vivo and in vitro cardiac muscle contraction via MUSCLEMOTION dataDownload

kindly provided by Nanion Technologies GmbH

Publications anchor

Publications

Hybrid Cell Analysis System to Assess Structural and Contractile Changes of Human iPSC-Derived Cardiomyocytes for Preclinical Cardiac Risk EvaluationDownload

2022 Journal of Visualized Experiments

Integration of mechanical conditioning into a high throughput contractility assay for cardiac safety assessmentDownload

2020 Journal of Pharmacological and Toxicological Methods

Higher throughput in vitro cardiac contractility recordings under physiological mechanical conditionsDownload

2019 FLEXcyte 96 Whitepaper

Mechano-Pharmacological Characterization of Cardiomyocytes Derived from Human Induced Pluripotent Stem CellsDownload

2016 Cellular Physiology and Biochemistry

Posters anchor

Posters

Assessment of a Smooth Muscle Cell Maturation Protocol for the Analysis of Contractile PropertiesDownload

2022 SPS Annual Meeting, Montréal, Canada

Lot-to-lot consistency study of commercial human iPSC derived cardiomyocytes regarding contractile propertiesDownload

2022 SPS Annual Meeting, Montréal, Canada

Tackling Chronic Compound Responses of hiPSC CMs for Preclinical Cardiac Risk Evaluation: Defined Serum Free Medium and Long Term Culture on the FLEXcyte 96 Download

2022 Biophysical Society Annual Meeting, San Francisco, USA

Physiological Versus Unphysiological Cell Culture Conditions: How The Environment Alters Gene Expression, Phenotype and Functional Properties of Human iPSC Derived CardiomyocytesDownload

2021 SPS Annual Meeting, virtual

Tackling Chronic Compound Responses of hiPSC-CMs for Preclinical Cardiac Risk Evaluation: Defined Serum-Free Medium and Long-Term Culture on the FLEXcyte96Download

2021 Nanion User Meeting, Munich

High Throughput Chronic Cardiotoxicity Evaluation of Human
iPSC Derived Cardiomyocytes in a Pro Maturation EnvironmentDownload

2021 Eurotox Annual Meeting, virtual

Chronic cardiac contractility assessment of human iPSC
derived cardiomyocytes in a pro maturation environment for preclinical cardiac safety and toxicity studiesDownload

2021 11th World Congress on Alternatives and Animal Use in Life Sciences, virtual

A physiological environment for human iPSC-derived cardiomyocytes facilitates maturation for reliable preclinical cardiac risk evaluation on high throughput levelDownload

2021 EUROoCS Annual Meeting, virtual

Chronic cardiotoxic effects of kinase inhibitors and anthracyclines on human iPSC derived cardiomyocytesDownload

2021 SOT Annual Meeting, virtual

Mechanical Stimulation in a 2D High-Throughput Contractility System Induces Functional Changes in Human Induced Pluripotent Stem Cell Derived CardiomyocytesDownload

2020 SPS Annual Meeting, virtual

Artificial Neural Networks in Cardiac Safety Assessment: Classification of Chemotherapeutic Compound Effects on hiPSC-Derived Cardiomyocyte ContractilityDownload

2020 SPS Annual Meeting , virtual

A Higher Throughput Approach to Investigate Cardiac Contractility In Vitro Under Physiological Mechanical ConditionsDownload

2019 SPS Annual Meeting, Barcelona, Spain

FLEXcyte: A New In Vitro Tool to Study Cardiac Contractility under Physiological Mechanical ConditionsDownload

2019 Nanion User Meeting, Boston, USA

presentations anchor

Presentations

Mechanobiology of in vitro assays: Tackling prevailing challanges in pre-clinical drug developmentDownload

2020 Annual Meeting of the Biophysical Society, San Diego

Mechanobiology of in vitro assays: Tackling prevailing challanges in pre-clinical drug developmentDownload

2019 Nanion User Meeting, Boston, MA

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Service Flyers

FLEXcyte 96 Cardiac Safety and Toxicity Service FlyerDownload
Contractile Force FlyerDownload
FLEXcyte Stimulation FlyerDownload

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