Order your quantitative phenotypic AtlaZ service to reveal the full spectrum of cell responses in a label-free and real-time monitoring manner.
With the AtlaZ system, we can accelerate your research by analyzing compound-induced effects of small molecules, biopharmaceuticals, vector-based or immune therapeutics on cellular level based on impedance technology. A large variety of cellular features can be monitored for several weeks simulataneously or separately on 6 x 96-well plates, including:
GPCR Analysis
Transepithelial Electrical Resistance (TEER)
Cell adhesion and Proliferation
Cell Monitoring
Cytolysis
Cytotoxicity
Immune cell-mediated killing of A549 cancer target cells
Cytolysis of A549 cancer target cells mediated by increasing effector T-cell ratios (E:T ratio 1:2, 1:1, 2:1, 3:1). Effector cells were added 24 h after target cell seeding. AtlaZ control software calculates cytolysis (%) as well as Kill time 50.
Kill time 50 of A549 cancer target cells. 50 % of cancer cells were killed by effector T-cells after 6 h at ratio 2:1 and 3:1 as well as after 13 h at ratio 1:1. Kill time 50 was not reached within 15 h at ratio 1:2. n=3-7.
Toxicity effects of human iPSC-derived cell types
Aflatoxin B1
Doxorubicin
Human iPSC-derived hepatocytes, cultured in 2D, show a concentration-dependent hepatotoxic effect upon Aflatoxin B1 treatment. Aflatoxin B1-mediated hepatotoxicity is a known effect in metabolically active hepatocytes.
Impedance recordings of human iPSC-derived cardiomyocytes show a concentration-dependent decrease of the base impedance in %, demonstrating structural cardiotoxicity when treated with doxorubicin.
Receive your tailored study report within 6 weeks
Each service is custom designed by an expert team in cooperation with the client. Owing to the unique Software, a fast and detailed analysis of the full frequence spectrum is performed and consolidated as end-to-end study report in less than 6 weeks.
