innoVation Series – Research Article of the Month – May 2021

We keep the focus on reviews this month, with one that has summarized current maturation methods for human induced pluripotent stem cell-derived cardiomyocytes.

Read the review to learn about maturity evaluation of human iPSC-derived cardiomyocytes in comparison to adult cardiomyocytes and how prolonged culture time, biochemical cues, cellular interaction, 3D cell-culture, and of course substrate stiffness and biophysical stimulation, are of importance to push human iPSC-derived cardiomyocyte maturation in vitro.

Find the article here