Real-time assessment of drug-induced human iPSC-cardiomyocyte structural changes
The electrical impedance spectroscopy of the CardioExcyte module reveals cell and monolayer integrity changes in real-time for up to seven days as a measure of acute and chronic cell activity. Compound-induced structural toxicity of human iPSC-cardiomyocytes can be assessed with a decrease in base impedance, as shown after nifedipine and doxorubicin treatment over a time span of 24 hours.
Analysis of electrophysiological properties with the electric field potential (EFP) parameter
The electrical impedance spectroscopy of the CardioExcyte module reveals cell and monolayer integrity changes in real-time for up to seven days as a measure of acute and chronic cell activity. Compound-induced structural toxicity of human iPSC-cardiomyocytes can be assessed with a decrease in base impedance, as shown after nifedipine and doxorubicin treatment over a time span of 24 hours.
Tailored study report covering all desired parameters
Each service is custom designed by an expert team in cooperation with the client. Owing to the applied Data Control Software, a fast and detailed analysis of impedance and EFP recordings is performed and consolidated as end-to-end study report in less than 6 weeks.
